All four sides will descend upon the Principality Stadium on Saturday for a bumper day of rugby as the Dragons face Scarlets before Cardiff Blues take on Ospreys.
So as the teams gear up for a crucial day of Guinness PRO14 action, we look back at some of the best moments Judgement Day has thrown up down the years.
North at the double: Judgement Day 2013
The inaugural Judgement Day kicked off in dramatic fashion as Scarlets overcame the Dragons 28-20 at Principality Stadium.
A win for Scarlets was essential for their hunt to make the semi-finals and they did just that with a dominant start at the national stadium.
George North crossed after 26 minutes before Jarrod Evans responded for the Dragons four minutes before the break.
Scarlets pulled away in the second-half thanks to a fine Jonathan Davies score before North sealed the victory with 12 minutes to go.
Webb wonder: Judgement Day 2016
Ospreys were looking to end their season on a high and did that in some style at Principality Stadium as they rallied back from 10 points down to claim their tenth consecutive win over Cardiff Blues.
This thriller looked to be heading the way of the Blues as Aled Summerhill dotted down and penalties from Gareth Anscombe helped the region into a commanding lead.
But Ospreys fired into life in the second half as Hanno Dirksen notched up a brace before Sam Underhill also got in on the act.
The final 10 minutes belonged to Rhys Webb, who crossed the whitewash twice to maintain Ospreys’ superb against over the Blues.
Blues sink Ospreys: Judgement Day 2017
Last season’s edition of Judgement Day had no shortage of drama.
Principality Stadium was the stage once again and 60,642 supporters packed the arena to watch Cardiff Blues down Ospreys 35-17.
The try-fest started after just five minutes when Kristian Dacey romped over before two tries from Lloyd Williams and Nick Williams had the Blues in complete control.
Gareth Anscombe secured the victory six minutes into the second half and despite late tries from Dan Evans and Paul James, Ospreys could not prevent their first ever defeat on Judgement Day.
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